产品货号：
Z36773
中文名称：
PARP1抗体
英文名称：
Anti-PARP1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PARP1 Antibody |
| 指标别名 | ADPRT;ADPRT 1;ADPRT1;pADPRT 1;PARP;PARP 1;PARP1;poly (ADP ribose) polymerase 1;Poly [ADP ribose] polymerase 1;Poly[ADP ribose] synthase 1;PPOL |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | PARP1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human PARP |
| 实际分子量 | 113KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Poly [ADP-ribose] polymerase 1 (PARP1),also known as ADPRT or PPOL is an enzyme that in humans is encoded by the PARP1 gene.PARP1 gene is mapped to 1q42.12.This gene encodes a chromatin-associated enzyme,poly(ADP-ribosyl)transferase,which modifies various nuclear proteins by poly(ADP-ribosyl)ation.The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation,proliferation,and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage.In addition,this enzyme may be the site of mutation in Fanconi anemia,and may participate in the pathophysiology of type I diabetes. |
| Uniprot ID | P09874 |
| 基因名全称 | Poly [ADP-ribose] polymerase 1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～200 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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